Insulin-like growth factor-binding protein 7

BE0002126ProteinHumansIGFBP7

Binds IGF1 and IGF2 with a relatively low affinity. It is acted on by 2 drugs in DrugBank.

Gene name
IGFBP7
UniProtKB entry
Q16270Swiss-Prot
Cellular location
Secreted
Residues / weight
282 residues · 29,130 Da
Also known as
IBP-7 · IGF-binding protein 7 · IGFBP-7 · IGFBP-rP1 · MAC25

Resolves to

Protein
UniProtQ16270UniProt nameIBP7_HUMAN
Gene
HGNCHGNC:5476NCBI Gene3490GenBank307151GeneCardsIGFBP7
Pharmacology
KEGGhsa:3490
Structure
PDB8IVD
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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13GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Insulin-like growth factor-binding protein 7, how selective are they, and which programs against it are still in active trials?

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