Pyridoxal phosphate homeostasis protein

BE0002149ProteinHumansPLPBP

Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6. It is acted on by 2 drugs in DrugBank.

Gene name
PLPBP
UniProtKB entry
O94903Swiss-Prot
Residues / weight
275 residues · 30,344 Da
Also known as
PLP homeostasis protein · Proline synthase co-transcribed bacterial homolog protein · PROSC · Pyridoxal phosphate-binding protein

Resolves to

Protein
UniProtO94903UniProt namePLPHP_HUMAN
Gene
HGNCHGNC:9457NCBI Gene11212GenBank4126978GeneCardsPLPBP
Pharmacology
KEGGhsa:11212
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Pyridoxal phosphate homeostasis protein, how selective are they, and which programs against it are still in active trials?

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