Choline/ethanolaminephosphotransferase 1

BE0002190ProteinHumansCEPT1

Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively (PubMed:10191259, PubMed:10893425, PubMed:12216837, PubMed:37137909). It is acted on by 2 drugs in DrugBank.

Gene name
CEPT1
UniProtKB entry
Q9Y6K0Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
416 residues · 46,553 Da
Also known as
1-alkenyl-2-acylglycerol choline phosphotransferase · 2.7.8.1 · 2.7.8.2 · hCEPT1

Resolves to

Protein
UniProtQ9Y6K0UniProt nameCEPT1_HUMAN
Gene
HGNCHGNC:24289NCBI Gene10390GenBank4584877GeneCardsCEPT1
Pharmacology
KEGGhsa:10390
Structure
PDB8GYWPDB8GYX
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Choline/ethanolaminephosphotransferase 1, how selective are they, and which programs against it are still in active trials?

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