Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

BE0002192ProteinHumansPLOD2

Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. It is acted on by 1 drug in DrugBank.

Gene name
PLOD2
UniProtKB entry
O00469Swiss-Prot
Cellular location
Rough endoplasmic reticulum membrane
Residues / weight
737 residues · 84,685 Da
Also known as
1.14.11.4 · LH2 · Lysyl hydroxylase 2

Resolves to

Protein
UniProtO00469UniProt namePLOD2_HUMAN
Gene
HGNCHGNC:9082NCBI Gene5352GenBank2138314GeneCardsPLOD2
Pharmacology
KEGGhsa:5352
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2, how selective are they, and which programs against it are still in active trials?

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