Protein-glutamine gamma-glutamyltransferase 6

BE0002239ProteinHumansTGM6

Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. It is acted on by 2 drugs in DrugBank.

Gene name
TGM6
UniProtKB entry
O95932Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
706 residues · 79,312 Da
Also known as
2.3.2.13 · TG6 · TGase Y · TGase-3-like · TGase-6

Resolves to

Protein
UniProtO95932UniProt nameTGM3L_HUMAN
Gene
HGNCHGNC:16255NCBI Gene343641GeneCardsTGM6
Pharmacology
KEGGhsa:343641
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
1Metabolic reactionDrug transformations it catalyses, substrate to product
Sign in
1GO termFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
7+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Protein-glutamine gamma-glutamyltransferase 6, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In