Methionine--tRNA ligase, mitochondrial

BE0002248ProteinHumansMARS2

Methionine--tRNA ligase, mitochondrial (Humans) is a protein target in DrugBank. It is acted on by 1 drug in DrugBank.

Gene name
MARS2
UniProtKB entry
Q96GW9Swiss-Prot
Cellular location
Mitochondrion matrix
Residues / weight
593 residues · 66,590 Da
Also known as
6.1.1.10 · Methionyl-tRNA synthetase 2 · Mitochondrial methionyl-tRNA synthetase · MtMetRS

Resolves to

Protein
UniProtQ96GW9UniProt nameSYMM_HUMAN
Gene
HGNCHGNC:25133NCBI Gene92935GenBank37196758GeneCardsMARS2
Pharmacology
KEGGhsa:92935
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Methionine--tRNA ligase, mitochondrial, how selective are they, and which programs against it are still in active trials?

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