S-methylmethionine--homocysteine S-methyltransferase BHMT2

BE0002249ProteinHumansBHMT2

Involved in the regulation of homocysteine metabolism. It is acted on by 1 drug in DrugBank.

Gene name
BHMT2
UniProtKB entry
Q9H2M3Swiss-Prot
Residues / weight
363 residues · 40,354 Da
Also known as
2.1.1.10 · Betaine--homocysteine S-methyltransferase 2 · SMM-hcy methyltransferase

Resolves to

Protein
UniProtQ9H2M3UniProt nameBHMT2_HUMAN
Gene
HGNCHGNC:1048NCBI Gene23743GenBank11907831GeneCardsBHMT2
Pharmacology
KEGGhsa:23743
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which approved drugs act on S-methylmethionine--homocysteine S-methyltransferase BHMT2, how selective are they, and which programs against it are still in active trials?

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