Excitatory amino acid transporter 5

BE0002267ProteinHumansSLC1A7

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. It is acted on by 1 drug in DrugBank.

Gene name
SLC1A7
UniProtKB entry
O00341Swiss-Prot
Cellular location
Photoreceptor inner segment membrane
Residues / weight
560 residues · 60,658 Da
Also known as
EAAT5 · Retinal glutamate transporter · Solute carrier family 1 member 7

Resolves to

Protein
UniProtO00341UniProt nameEAA5_HUMAN
Gene
HGNCHGNC:10945NCBI Gene6512GenBank2076762GeneCardsSLC1A7
Pharmacology
IUPHAR/GtoPdb872KEGGhsa:6512
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Excitatory amino acid transporter 5, how selective are they, and which programs against it are still in active trials?

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