Excitatory amino acid transporter 4

BE0002270ProteinHumansSLC1A6

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:26690923, PubMed:7791878). It is acted on by 1 drug in DrugBank.

Gene name
SLC1A6
UniProtKB entry
P48664Swiss-Prot
Cellular location
Cell membrane
Residues / weight
564 residues · 61,565 Da
Also known as
EAAT4 · Sodium-dependent glutamate/aspartate transporter · Solute carrier family 1 member 6

Resolves to

Protein
UniProtP48664UniProt nameEAA4_HUMAN
Gene
HGNCHGNC:10944NCBI Gene6511GenBank930337GeneCardsSLC1A6
Pharmacology
IUPHAR/GtoPdb871KEGGhsa:6511
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
14GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
5+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Excitatory amino acid transporter 4, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In