Glutaredoxin-1

BE0002284ProteinHumansGLRX

Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. It is acted on by 2 drugs in DrugBank.

Gene name
GLRX
UniProtKB entry
P35754Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
106 residues · 11,776 Da
Also known as
GRX · Thioltransferase-1 · TTase-1

Resolves to

Protein
UniProtP35754UniProt nameGLRX1_HUMAN
Gene
HGNCHGNC:4330NCBI Gene2745GenBank643695GeneCardsGLRX
Pharmacology
KEGGhsa:2745
Structure
PDB1B4QPDB1JHBPDB4RQR
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutaredoxin-1, how selective are they, and which programs against it are still in active trials?

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