PRO 2000 is an investigational medicine that is not yet approved by the FDA for use outside of clinical trials. It is being studied for the prevention of HIV infection... This medicine does not cure HIV infection or AIDS and is being studied to reduce the risk of passing the virus to other people.
- Mechanism
- Curator reviewed
PRO 2000, also known as PRO 2000/5, is a type of medicine called a microbicide. Microbicides are substances that protect the body from infection by microorganisms such as bacteria, viruses, and fungi. Microbicides work by either destroying the microbes or preventing them from establishing an infection.
PRO 2000 is a candidate topical microbicide for the prevention of sexually transmitted infections including infection by the Human Immunodeficiency Virus (HIV), the cause of Acquired Immunodeficiency Syndrome (AIDS). The compound is believed to block the entry of sexually transmitted disease (STD) pathogens into human cells. In addition to its demonstrated activity against HIV infection in laboratory tests and animal models, PRO 2000 has been shown to be active against other STD pathogens such as herpes, chlamydia, and the bacterium that causes gonorrhea. Designed to be applied vaginally prior to sexual intercourse, PRO 2000 promises to offer a discreet "safer sex" option that can be controlled by women.
- Primary indication
- Investigated for use/treatment in HIV prevention, prevention of stdis, and vaginal infection.Curator reviewed
- Also known as
- Polynaphthalene sulphonate
- Code names
- Pro 1041 · PRO-2000 · PRO 2000/5
Resolves to
What you can answer from here — as of July 03, 2026
Which drugs share a target with PRO 2000, and which of those have an active Phase 3 trial?
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