Glutathione S-transferase Mu 5

BE0002285ProteinHumansGSTM5

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. It is acted on by 2 drugs in DrugBank.

Gene name
GSTM5
UniProtKB entry
P46439Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
218 residues · 25,674 Da
Also known as
2.5.1.18 · GST class-mu 5 · GSTM5-5

Resolves to

Protein
UniProtP46439UniProt nameGSTM5_HUMAN
Gene
HGNCHGNC:4637NCBI Gene2949GenBank468260GeneCardsGSTM5
Pharmacology
KEGGhsa:2949
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutathione S-transferase Mu 5, how selective are they, and which programs against it are still in active trials?

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