PF-06651600

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name: PF-06651600
DrugBank Accession Number: DB14924
Background: PF-06651600 is under investigation in clinical trial NCT02974868 (Study To Evaluate The Efficacy And Safety Profile Of PF-06651600 And PF-06700841 In Subjects With Alopecia Areata).
Type: Small Molecule
Groups: Investigational
Structure: 3D
MOL SDF 3D-SDF PDB SMILES InChI

Similar Structures
Structure for PF-06651600 (DB14924)
Synonyms: Not Available

Indication: Not Available
Reduce drug development failure rates
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Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half-life: Not Available
Clearance: Not Available
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Toxicity: Not Available
Pathways: Not Available
Pharmacogenomic Effects/ADRs: Not Available

Drug Interactions: This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions: Not Available

UNII: 2OYE00PC25
CAS number: 1792180-81-4
InChI Key: CBRJPFGIXUFMTM-WDEREUQCSA-N
InChI: InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
IUPAC Name: 1-[(2S,5R)-2-methyl-5-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)piperidin-1-yl]prop-2-en-1-one
SMILES: C[C@H]1CC[C@H](CN1C(=O)C=C)NC1=NC=NC2=C1C=CN2

General References

Not Available

External Links

Clinical Trials

Phase	Status	Purpose	Conditions	Count
3	Active Not Recruiting	Treatment	Alopecia Areata (AA)	1
2	Active Not Recruiting	Other	Alopecia Areata (AA)	1
2	Completed	Treatment	Active Non-segmental Vitiligo	1
2	Completed	Treatment	Alopecia Areata (AA)	1
2	Completed	Treatment	Rheumatoid Arthritis	2
2	Completed	Treatment	Ulcerative Colitis	1
2	Recruiting	Treatment	Crohn's Disease (CD)	1
2, 3	Completed	Treatment	Alopecia Areata (AA)	1
1	Completed	Basic Science	Healthy Females	1
1	Completed	Basic Science	Healthy Subjects (HS)	14

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Predicted ADMET Features

Not Available

Drug created at May 20, 2019 14:35 / Updated at June 12, 2020 16:53