Protein-arginine deiminase type-1

BE0002314ProteinHumansPADI1

Catalyzes the deimination of arginine residues of proteins. It is acted on by 2 drugs in DrugBank.

Gene name
PADI1
UniProtKB entry
Q9ULC6Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
663 residues · 74,665 Da
Also known as
3.5.3.15 · PAD1 · PDI1 · Peptidylarginine deiminase I · Protein-arginine deiminase type I

Resolves to

Protein
UniProtQ9ULC6UniProt namePADI1_HUMAN
Gene
HGNCHGNC:18367NCBI Gene29943GenBank6116899GeneCardsPADI1
Pharmacology
IUPHAR/GtoPdb2894KEGGhsa:29943
Structure
PDB5HP5
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Protein-arginine deiminase type-1, and which indications are they being tested in?

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