Peptidyl-prolyl cis-trans isomerase C

BE0002333ProteinHumansPPIC

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. It is acted on by 1 drug in DrugBank.

Gene name
PPIC
UniProtKB entry
P45877Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
212 residues · 22,763 Da
Also known as
5.2.1.8 · Cyclophilin C · CYPC · PPIase C · Rotamase C

Resolves to

Pharmacology
Structure

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Peptidyl-prolyl cis-trans isomerase C, how selective are they, and which programs against it are still in active trials?

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