Pyruvate:flavodoxin oxidoreductase

BE0002361ProteinEscherichia coli (strain K12)ydbK

Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. It is acted on by 1 drug in DrugBank.

Gene name
ydbK
UniProtKB entry
P52647Swiss-Prot
Residues / weight
1,174 residues · 128,823 Da
Also known as
1.2.7.- · 1.2.8.1 · CoA-acylating pyruvate:flavodoxin oxidoreductase · PFOR · Probable pyruvate-flavodoxin oxidoreductase

Resolves to

Protein
UniProtP52647UniProt nameYDBK_ECOLI
Gene
NCBI Gene946587GenBank1787642
Pharmacology
KEGGecj:JW1372
Drugs

What you can answer from here — as of June 11, 2026

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Pyruvate:flavodoxin oxidoreductase, how selective are they, and which programs against it are still in active trials?

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