Arachidonate 5-lipoxygenase-activating protein

BE0002382ProteinHumansALOX5AP

Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). It is acted on by 6 drugs in DrugBank.

Gene name
ALOX5AP
UniProtKB entry
P20292Swiss-Prot
Cellular location
Nucleus membrane
Residues / weight
161 residues · 18,157 Da
Also known as
FLAP · MK-886-binding protein

Resolves to

Protein
UniProtP20292UniProt nameAL5AP_HUMAN
Gene
HGNCHGNC:436NCBI Gene241GeneCardsALOX5AP
Pharmacology
KEGGhsa:241
Structure
PDB2Q7MPDB2Q7RPDB6VGC
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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35+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Arachidonate 5-lipoxygenase-activating protein, and which indications are they being tested in?

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