Atuliflapon

DB19029InvestigationalSmall molecule

Atuliflapon is under investigation in clinical trial NCT05251259 (Study to Assess the Efficacy and Safety of Atuliflapon in Moderate-to-severe Uncontrolled Asthma).

Mechanism: Pharmacologically active on Arachidonate 5-lipoxygenase-activating protein
Curator reviewed
Formula / weight: C₂₄H₂₆N₆O₃ · 446.511 g/mol (avg)
Also known as: (1r,2r)-2-(4-(3-methyl-1h-pyrazol-5-yl)benzoyl)-n-(4-oxo-6,7-dihydro-5h-pyrazolo(1,5-a)pyrazine-3-yl)cyclohexanecarboxamide · Cyclohexanecarboxamide, 2-(4-(5-methyl-1h-pyrazol-3-yl)benzoyl)-n-(4,5,6,7-tetrahydro-4-oxopyrazolo(1,5-a)pyrazin-3-yl)-, (1r,2r)-
Code names: AZD-5718

Resolves to

Compound

UNIINV6352Y6TVCAS2041075-86-7ChEMBLCHEMBL4542281

Structure

InChIKeyROTWSDMXHVGAHZ-QZTJIDSGSA-NSMILESCC1=NNC(=C1)C1=CC=C(C=C1)C(=O)[C@@H]1CCCC[C@H]1C(=O)NC1=C2N(CCNC2=O)N=C1

Targets

P20292ALOX5AP

What you can answer from here — as of July 09, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

10Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Atuliflapon, and which of those have an active Phase 3 trial?

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