Penicillin-binding protein 2x

BE0002392ProteinStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)pbpX

A transpeptidase that forms peptide cross-links between adjacent glycan strands in cell wall peptidoglycan (PG). It is acted on by 3 drugs in DrugBank.

Gene name
pbpX
UniProtKB entry
P14677Swiss-Prot
Cellular location
Cell membrane
Residues / weight
750 residues · 82,312 Da
Also known as
PBP-2x

Resolves to

Protein
UniProtP14677UniProt namePBPX_STRPN
Pharmacology
KEGGspn:SP_0336
Structure
PDB1PMDPDB1QMEPDB1QMF
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Penicillin-binding protein 2x, how selective are they, and which programs against it are still in active trials?

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