Ceftaroline fosamil

DB06590ApprovedInvestigationalSmall moleculeCephalosporins

Ceftaroline fosamil is an antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia.

Mechanism: Ceftaroline fosamil is an antibacterial drug.
Curator reviewed
Primary indication: Ceftaroline fosamil is indicated for the treatment of patients with the following infections caused by susceptible isolates of the designated microorganisms.Curator reviewed · 3 structured indications
Formula / weight: C₂₂H₂₁N₈O₈PS₄ · 684.67 g/mol (avg)
First approval: United States, 2010 · European Union, 2016
Also known as: Ceftaroline
Code names: PPI-0903 · TAK-599
Brand names: Teflaro
Zinforo

Resolves to

Compound

UNII7P6FQA5D21CAS229016-73-3ChEMBLCHEMBL501122ChEBI70718PubChem9852981KEGGD08884

Clinical / RWD

RxNorm1040004ATCJ01DI02

Structure

InChIKeyZCCUWMICIWSJIX-NQJJCJBVSA-NSMILES[H][C@]12SCC(SC3=NC(=CS3)C3=CC=[N+](C)C=C3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OCC)\C1=NSC(NP(O)(O)=O)=N1)C([O-])=O

Targets

P14677pbpXQ53707mecA

What you can answer from here — as of September 12, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1,153Drug interactionsStructured to mechanism, not free text

45Clinical trialsPhase, status and sponsor resolved per trial

3Structured indicationsCondition, population, route and combination as fields, not prose

1ContraindicationEach with its own population and attribute set

13Marketed productsAcross 9 countries and 7 labellers

1ATC codeIncluding every combination product, plus 15 drug categories

11+ReferencesStructured and connected to the statements they support

Which drugs share a target with Ceftaroline fosamil, and which of those have an active Phase 3 trial?

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