Neuropeptide Y receptor type 2

BE0002419ProteinHumansNPY2R

Receptor for neuropeptide Y (NPY) and peptide YY (PYY) (PubMed:7592910, PubMed:7559383, PubMed:35507650, PubMed:36525977, PubMed:38882210). It is acted on by 5 drugs in DrugBank.

Gene name
NPY2R
UniProtKB entry
P49146Swiss-Prot
Cellular location
Cell membrane
Residues / weight
381 residues · 42,731 Da
Also known as
NPY-Y2 receptor · NPY2-R · Y2 receptor

Resolves to

Protein
UniProtP49146UniProt nameNPY2R_HUMAN
Gene
HGNCHGNC:7957NCBI Gene4887GeneCardsNPY2R
Pharmacology
IUPHAR/GtoPdb306KEGGhsa:4887
Structure
PDB7DDZPDB7X9BPDB7YON
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Neuropeptide Y receptor type 2, how selective are they, and which programs against it are still in active trials?

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