Interleukin-4 receptor subunit alpha

BE0002420ProteinHumansIL4R

Receptor for both interleukin 4 and interleukin 13 (PubMed:17030238). It is acted on by 6 drugs in DrugBank.

Gene name
IL4R
UniProtKB entry
P24394Swiss-Prot
Cellular location
Cell membrane
Residues / weight
825 residues · 89,657 Da
Also known as
IL-4 receptor subunit alpha · IL-4R subunit alpha · IL-4R-alpha · IL-4RA · IL4RA

Resolves to

Protein
UniProtP24394UniProt nameIL4RA_HUMAN
Gene
HGNCHGNC:6015NCBI Gene3566GeneCardsIL4R
Pharmacology
IUPHAR/GtoPdb1697KEGGhsa:3566
Structure
PDB1IARPDB1IRSPDB3BPL
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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43+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Interleukin-4 receptor subunit alpha, how selective are they, and which programs against it are still in active trials?

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