Histamine N-methyltransferase

BE0002436ProteinHumansHNMT

Inactivates histamine by N-methylation. It is acted on by 8 drugs in DrugBank.

Gene name
HNMT
UniProtKB entry
P50135Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
292 residues · 33,295 Da
Also known as
2.1.1.8 · HMT

Resolves to

Protein
UniProtP50135UniProt nameHNMT_HUMAN
Gene
HGNCHGNC:5028NCBI Gene3176GeneCardsHNMT
Pharmacology
KEGGhsa:3176
Structure
PDB1JQDPDB1JQEPDB2AOT
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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34+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Histamine N-methyltransferase, how selective are they, and which programs against it are still in active trials?

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