Non-selective voltage-gated ion channel VDAC2

BE0002469ProteinHumansVDAC2

Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane and plasma membrane (PubMed:8420959). It is acted on by 3 drugs in DrugBank.

Gene name
VDAC2
UniProtKB entry
P45880Swiss-Prot
Cellular location
Mitochondrion outer membrane
Residues / weight
294 residues · 31,566 Da
Also known as
hVDAC2 · Outer mitochondrial membrane protein porin 2 · VDAC-2

Resolves to

Protein
UniProtP45880UniProt nameVDAC2_HUMAN
Gene
HGNCHGNC:12672NCBI Gene7417GeneCardsVDAC2
Pharmacology
KEGGhsa:7417
Structure
PDB9EIHPDB9EIIPDB9EIJ
Drugs

What you can answer from here — as of February 11, 2025

3DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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21+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Non-selective voltage-gated ion channel VDAC2, and which indications are they being tested in?

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