Non-selective voltage-gated ion channel VDAC3

BE0002470ProteinHumansVDAC3

Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane and plasma membrane (PubMed:31935282). It is acted on by 2 drugs in DrugBank.

Gene name
VDAC3
UniProtKB entry
Q9Y277Swiss-Prot
Cellular location
Mitochondrion outer membrane
Residues / weight
283 residues · 30,658 Da
Also known as
hVDAC3 · Outer mitochondrial membrane protein porin 3 · VDAC-3

Resolves to

Protein
UniProtQ9Y277UniProt nameVDAC3_HUMAN
Gene
HGNCHGNC:12674NCBI Gene7419GeneCardsVDAC3
Pharmacology
KEGGhsa:7419
Drugs

What you can answer from here — as of February 11, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Non-selective voltage-gated ion channel VDAC3, and which indications are they being tested in?

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