alpha-L-fucosidase

BE0002483ProteinThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. It is acted on by 2 drugs in DrugBank.

UniProtKB entry: Q9WYE2TrEMBL
Cellular location: Cytoplasmic
Residues / weight: 449 residues · 52,205 Da
Also known as: 3.2.1.51 · Alpha-L-fucosidase, putative

Resolves to

Protein

UniProtQ9WYE2UniProt nameQ9WYE2_THEMA

Gene

NCBI Gene897238

Pharmacology

KEGGtma:TM0306

Structure

PDB1HL8PDB1HL9PDB1ODU

Drugs

What you can answer from here — as of February 03, 2026

2DrugsApproved to experimental, with action, bond type and pharmacological action

2GO termsFunction, process and component, as structured annotations

2Pfam domainsDomain architecture mapped to Pfam families and clans

4+ReferencesStructured and connected to the statements they support

Which compounds in development act on alpha-L-fucosidase, and which indications are they being tested in?

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