Interleukin-10

BE0002484ProteinHumansIL10

Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. It is acted on by 3 drugs in DrugBank.

Gene name
IL10
UniProtKB entry
P22301Swiss-Prot
Cellular location
Secreted
Residues / weight
178 residues · 20,517 Da
Also known as
CSIF · Cytokine synthesis inhibitory factor · IL-10

Resolves to

Protein
UniProtP22301UniProt nameIL10_HUMAN
Gene
HGNCHGNC:5962NCBI Gene3586GeneCardsIL10
Pharmacology
KEGGhsa:3586
Structure
PDB1ILKPDB1INRPDB1J7V
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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57Clinical trialsTrials of drugs acting on it, by phase and status
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38GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Interleukin-10, and which indications are they being tested in?

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