Hypoxanthine phosphoribosyltransferase

BE0002488ProteinTrypanosoma cruziHGPRTase

Hypoxanthine phosphoribosyltransferase (Trypanosoma cruzi) is a protein target in DrugBank. It is acted on by 4 drugs in DrugBank.

Gene name
HGPRTase
UniProtKB entry
Q27796TrEMBL
Cellular location
Cytoplasm (By similarity)
Residues / weight
221 residues · 25,529 Da
Also known as
2.4.2.8 · EC 2.4.2.8 · Hypoxanthine-guanine phosphoribosyltransferase

Resolves to

Protein
UniProtQ27796UniProt nameQ27796_TRYCR
Drugs

What you can answer from here — as of May 03, 2025

4DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Hypoxanthine phosphoribosyltransferase, how selective are they, and which programs against it are still in active trials?

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