Anthranilate phosphoribosyltransferase

BE0002489ProteinErwinia carotovoratrpD

Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA). It is acted on by 1 drug in DrugBank.

Gene name
trpD
UniProtKB entry
Q8VP84TrEMBL
Residues / weight
345 residues · 37,018 Da
Also known as
2.4.2.18

Resolves to

Protein
UniProtQ8VP84UniProt nameQ8VP84_PECCA
Structure
PDB1KGZPDB1KHD
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
1+ReferenceStructured and connected to the statements they support
Sign in

Which approved drugs act on Anthranilate phosphoribosyltransferase, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In