Anthranilate phosphoribosyltransferase
Details
- Name
- Anthranilate phosphoribosyltransferase
- Kind
- protein
- Synonyms
- 2.4.2.18
- Gene Name
- trpD
- UniProtKB Entry
- Q8VP84TrEMBL
- Organism
- Pectobacterium carotovorum
- NCBI Taxonomy ID
- 554
- Amino acid sequence
>lcl|BSEQ0021992|Anthranilate phosphoribosyltransferase MQATLIKPTIFTHQPILEKLFKSQSMTQEESHQLFAAIVRGELEDSQLAAALISMKMRGE RPEEIAGAASALLADAQPFPRPDYDFADIVGTGGDGTNSINISTASAFVAASCGAKVAKH GNRSVCQPLAGSCDLLQAFGIRLDMSAEDSRQALDDLNVCFLFAPQYHTGFRHAMPVRQQ LKTRTIFNVLGPLINPARPPKALIGVYSPELVLPIAQALKVLGYKNAAVVHGGGMDEVAI HTPTQVAELNNGEIESYQLSPQDFGLQSYSLNALQGGTPEENRDILARLLQGKGDAAHAR QVAANVALLLKLFGQDNLRHNAQLALETIRSGTAFERVTALAARG
- Number of residues
- 345
- Molecular Weight
- 37017.84
- Theoretical pI
- 6.6
- GO Classification
- Functionsanthranilate phosphoribosyltransferase activity / magnesium ion bindingProcessestryptophan biosynthetic process
- General Function
- Magnesium ion binding
- Specific Function
- Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
- Pfam Domain Function
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0004887|1038 bp ATGCAAGCCACATTGATCAAACCAACTATTTTTACGCATCAGCCTATTTTAGAAAAACTG TTCAAATCGCAGTCGATGACGCAAGAAGAAAGCCACCAGCTATTTGCCGCTATCGTGCGC GGTGAGTTAGAAGACAGCCAACTGGCAGCGGCGCTGATTAGCATGAAAATGCGCGGTGAA CGTCCTGAAGAAATTGCGGGGGCTGCCAGCGCCCTATTGGCTGATGCTCAACCGTTCCCG CGCCCAGACTATGACTTTGCGGATATCGTAGGCACCGGCGGCGACGGTACGAACAGCATC AACATCTCTACCGCGAGCGCTTTTGTCGCGGCCAGCTGCGGCGCTAAAGTGGCTAAACAT GGCAACCGCAGCGTTTGCCAGCCGTTGGCAGGATCGTGTGATTTATTACAGGCCTTTGGC ATTCGCTTAGACATGAGCGCCGAAGATTCACGCCAAGCGCTGGATGATTTAAATGTCTGT TTCCTGTTTGCGCCGCAGTATCACACCGGTTTTCGCCACGCGATGCCGGTTCGCCAACAG CTGAAAACCCGCACCATTTTTAACGTGCTCGGCCCACTGATTAACCCTGCGCGTCCACCT AAGGCCCTGATCGGCGTTTACAGCCCTGAATTGGTGTTGCCGATTGCTCAGGCGCTAAAA GTGTTGGGCTATAAGAATGCCGCGGTGGTTCACGGGGGTGGAATGGACGAAGTGGCTATT CACACCCCGACGCAGGTGGCTGAGTTAAACAACGGTGAAATCGAAAGCTATCAGCTTTCT CCGCAAGATTTTGGCTTACAGAGTTATTCGCTAAATGCGTTACAAGGCGGAACCCCAGAA GAAAATCGTGACATTCTGGCGCGCTTATTACAAGGTAAAGGTGATGCAGCGCACGCTCGG CAGGTCGCCGCTAACGTAGCTTTGCTGTTGAAATTGTTCGGTCAGGATAATCTGCGCCAC AACGCGCAACTGGCACTGGAAACCATCAGAAGCGGGACAGCATTTGAGCGAGTGACCGCA TTGGCAGCACGAGGCTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q8VP84 UniProtKB Entry Name Q8VP84_PECCA GenBank Gene ID AY064465 PDB ID(s) 1KGZ, 1KHD - General References
- Kim C, Xuong NH, Edwards S, Madhusudan, Yee MC, Spraggon G, Mills SE: The crystal structure of anthranilate phosphoribosyltransferase from the enterobacterium Pectobacterium carotovorum. FEBS Lett. 2002 Jul 17;523(1-3):239-46. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details 5-O-phosphono-alpha-D-ribofuranosyl diphosphate approved, experimental, investigational unknown target Details