Glucose-1-phosphate thymidylyltransferase

BE0002493ProteinPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)rmlA

Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. It is acted on by 6 drugs in DrugBank.

Gene name
rmlA
UniProtKB entry
Q9HU22TrEMBL
Residues / weight
293 residues · 32,457 Da
Also known as
2.7.7.24

Resolves to

Protein
UniProtQ9HU22UniProt nameQ9HU22_PSEAE
Gene
NCBI Gene879990
Pharmacology
KEGGpae:PA5163
Structure
PDB1FXOPDB1FZWPDB1G0R
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glucose-1-phosphate thymidylyltransferase, how selective are they, and which programs against it are still in active trials?

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