Ribosomal RNA small subunit methyltransferase H

BE0002515ProteinThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)rsmH

Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. It is acted on by 1 drug in DrugBank.

Gene name
rsmH
UniProtKB entry
Q9WZX6Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
299 residues · 34,893 Da
Also known as
16S rRNA m(4)C1402 methyltransferase · 2.1.1.199 · mraW · rRNA (cytosine-N(4)-)-methyltransferase RsmH

Resolves to

Protein
UniProtQ9WZX6UniProt nameRSMH_THEMA
Gene
NCBI Gene898545
Pharmacology
KEGGtma:TM0872
Structure
PDB1M6YPDB1N2X
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Ribosomal RNA small subunit methyltransferase H, and which indications are they being tested in?

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