Cyclopropane mycolic acid synthase 3

BE0002521ProteinMycobacterium tuberculosispcaA

Involved in the phagosome maturation block (PMB). It is acted on by 2 drugs in DrugBank.

Gene name
pcaA
UniProtKB entry
P9WPB3Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
287 residues · 33,028 Da
Also known as
2.1.1.79 · AdoMet-MT · CFA synthase · cma3 · cmaA3

Resolves to

Protein
UniProtP9WPB3UniProt nameCMAS3_MYCTU
Gene
NCBI Gene886284
Pharmacology
KEGGmtu:Rv0470c
Structure
PDB1L1E
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cyclopropane mycolic acid synthase 3, how selective are they, and which programs against it are still in active trials?

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