tRNA (guanine-N(1)-)-methyltransferase

BE0002525ProteinHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)trmD

Specifically methylates guanosine-37 in various tRNAs. It is acted on by 1 drug in DrugBank.

Gene name
trmD
UniProtKB entry
P43912Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
246 residues · 27,542 Da
Also known as
2.1.1.228 · M1G-methyltransferase · tRNA [GM37] methyltransferase

Resolves to

Protein
UniProtP43912UniProt nameTRMD_HAEIN
Gene
NCBI Gene951111
Pharmacology
KEGGhin:HI0202
Structure
PDB1UAJPDB1UAKPDB1UAL
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
2GO termsFunction, process and component, as structured annotations
Sign in
2+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on tRNA (guanine-N(1)-)-methyltransferase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In