tRNA (guanine-N(1)-)-methyltransferase

BE0002527ProteinShigella flexneritrmD

Specifically methylates guanosine-37 in various tRNAs. It is acted on by 1 drug in DrugBank.

Gene name
trmD
UniProtKB entry
P0A876Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
255 residues · 28,422 Da
Also known as
2.1.1.228 · M1G-methyltransferase · tRNA [GM37] methyltransferase

Resolves to

Protein
UniProtP0A876UniProt nameTRMD_SHIFL
Gene
NCBI Gene1025670
Pharmacology
KEGGsfl:SF2667
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on tRNA (guanine-N(1)-)-methyltransferase, and which indications are they being tested in?

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