ADP-ribose pyrophosphatase

Details

Name
ADP-ribose pyrophosphatase
Kind
protein
Synonyms
Not Available
Gene Name
ndx4
UniProtKB Entry
Q84CU3TrEMBL
Organism
Thermus thermophilus
NCBI Taxonomy ID
274
Amino acid sequence
>lcl|BSEQ0011813|ADP-ribose pyrophosphatase
MGRVYYGGVERTYLYRGRILNLALEGRYEIVEHKPAVAVIALREGRMLFVRQMRPAVGLA
PLEIPAGLIEPGEDPLEAARRELAEETGLSGDLTYLFSYFVSPGFTDEKTHVFLAENLKE
VEAHPDEDEAIEVVWMRPEEALERHQRGEVEFSATGLVGVLYYHAFLRGR
Number of residues
170
Molecular Weight
19263.785
Theoretical pI
4.75
GO Classification
Functions
hydrolase activity / nucleotide binding
General Function
Nucleotide binding
Specific Function
Not Available
Pfam Domain Function
Signal Regions
Not Available
Transmembrane Regions
Not Available
Cellular Location
Not Available
Gene sequence
>lcl|BSEQ0011814|ADP-ribose pyrophosphatase (ndx4)
ATGGGAAGAGTCTATTATGGGGGCGTGGAACGCACCTACCTCTACCGGGGCCGCATCCTG
AACCTGGCCCTGGAAGGCCGTTACGAGATCGTGGAACACAAGCCCGCCGTGGCGGTGATC
GCCCTGCGGGAAGGGAGGATGCTCTTCGTGCGCCAGATGCGCCCCGCCGTGGGCCTCGCC
CCCCTGGAGATCCCGGCGGGCCTCATAGAGCCCGGGGAGGACCCCTTGGAGGCGGCGAGG
AGGGAGCTCGCCGAGGAGACGGGCCTTAGCGGGGACCTCACCTACCTCTTCAGTTACTTC
GTCTCCCCCGGCTTCACCGACGAGAAGACCCACGTCTTCCTCGCGGAAAACCTAAAGGAG
GTGGAGGCCCACCCCGACGAGGACGAGGCCATAGAGGTGGTCTGGATGCGCCCGGAGGAG
GCCCTAGAGAGGCACCAGAGGGGGGAGGTGGAGTTCTCGGCCACGGGGCTCGTGGGGGTC
CTCTACTACCATGCTTTTCTCCGAGGTCGCTGA
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDQ84CU3
UniProtKB Entry NameQ84CU3_THETH
GenBank Gene IDAB107660
PDB ID(s)1V8I, 1V8L, 1V8M, 1V8N, 1V8R, 1V8S, 1V8T, 1V8U, 1V8V, 1V8W, 1V8Y
KEGG IDttj:TTHA0528
NCBI Gene ID3169402
General References
  1. Yoshiba S, Ooga T, Nakagawa N, Shibata T, Inoue Y, Yokoyama S, Kuramitsu S, Masui R: Structural insights into the Thermus thermophilus ADP-ribose pyrophosphatase mechanism via crystal structures with the bound substrate and metal. J Biol Chem. 2004 Aug 27;279(35):37163-74. Epub 2004 Jun 21. [Article]

Associated Data

Drug Relations
DrugDrug groupPharmacological action?TypeActionsDetails
Ribose-5-phosphateexperimentalunknowntargetDetails
Adenosine-5-DiphosphoriboseexperimentalunknowntargetDetails