FMN-dependent NADH:quinone oxidoreductase

BE0002577ProteinEscherichia coli (strain K12)azoR

Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. It is acted on by 2 drugs in DrugBank.

Gene name
azoR
UniProtKB entry
P41407Swiss-Prot
Residues / weight
201 residues · 21,657 Da
Also known as
1.6.5.- · 1.7.-.- · acpD · Azo-dye reductase · FMN-dependent NADH-azo compound oxidoreductase

Resolves to

Protein
UniProtP41407UniProt nameAZOR_ECOLI
Gene
NCBI Gene947569
Pharmacology
KEGGecj:JW1409
Structure
PDB1TIKPDB1V4BPDB2D5I
Drugs

What you can answer from here — as of May 03, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
8GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
8+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on FMN-dependent NADH:quinone oxidoreductase, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In