Diacetyl reductase [(S)-acetoin forming]

BE0002635ProteinKlebsiella pneumoniaebudC

Catalyzes the reversible reduction of (S)-acetoin to 2,3-butanediol in the presence of NADH. It is acted on by 1 drug in DrugBank.

Gene name
budC
UniProtKB entry
Q48436Swiss-Prot
Residues / weight
256 residues · 26,642 Da
Also known as
1.1.1.304 · Acetoin(diacetyl) reductase · AR · Meso-2,3-butanediol dehydrogenase

Resolves to

Protein
UniProtQ48436UniProt nameBUDC_KLEPN
Structure
PDB1GEGPDB3WYE
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Diacetyl reductase [(S)-acetoin forming], and which indications are they being tested in?

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