Histone acetyltransferase KAT2B

BE0002683ProteinHumansKAT2B

Functions as a histone acetyltransferase (HAT) to promote transcriptional activation (PubMed:8945521). It is acted on by 4 drugs in DrugBank.

Gene name
KAT2B
UniProtKB entry
Q92831Swiss-Prot
Cellular location
Nucleus
Residues / weight
832 residues · 93,012 Da
Also known as
2.3.1.48 · Histone acetylase PCAF · Histone acetyltransferase PCAF · Lysine acetyltransferase 2B · P/CAF

Resolves to

Protein
UniProtQ92831UniProt nameKAT2B_HUMAN
Gene
HGNCHGNC:8638NCBI Gene8850GeneCardsKAT2B
Pharmacology
IUPHAR/GtoPdb2737KEGGhsa:8850
Structure
PDB1CM0PDB1JM4PDB1N72
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
1Clinical trialTrials of drugs acting on it, by phase and status
Sign in
24GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
26+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Histone acetyltransferase KAT2B, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In