Purine nucleoside phosphorylase

BE0002734ProteinThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. It is acted on by 1 drug in DrugBank.

UniProtKB entry
Q9X1T2TrEMBL
Residues / weight
265 residues · 29,173 Da
Also known as
2.4.2.1 · Inosine-guanosine phosphorylase

Resolves to

Protein
UniProtQ9X1T2UniProt nameQ9X1T2_THEMA
Gene
NCBI Gene897943
Pharmacology
KEGGtma:TM1596
Structure
PDB1VMK
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
2GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
2+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Purine nucleoside phosphorylase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In