Levansucrase

BE0002788ProteinBacillus subtilis (strain 168)sacB

Catalyzes the synthesis of levan, a fructose polymer, by transferring the fructosyl moiety from sucrose to a growing acceptor molecule (PubMed:14517548, PubMed:18596022, PubMed:32553967, PubMed:33303628, PubMed:4206083). It is acted on by 1 drug in DrugBank.

Gene name
sacB
UniProtKB entry
P05655Swiss-Prot
Cellular location
Secreted
Residues / weight
473 residues · 52,971 Da
Also known as
2.4.1.10 · Beta-D-fructofuranosyl transferase · Fructosyltransferase · FTF · Sucrose 6-fructosyl transferase

Resolves to

Protein
UniProtP05655UniProt nameLSC_BACSU
Gene
NCBI Gene936413
Pharmacology
KEGGbsu:BSU34450
Structure
PDB1OYGPDB1PT2PDB2VDT
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Levansucrase, how selective are they, and which programs against it are still in active trials?

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