Sucrose
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Identification
- Generic Name
- Sucrose
- DrugBank Accession Number
- DB02772
- Background
A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener.
- Type
- Small Molecule
- Groups
- Approved, Experimental, Investigational
- Structure
- Weight
- Average: 342.2965
Monoisotopic: 342.116211546 - Chemical Formula
- C12H22O11
- Synonyms
- 1-alpha-D-Glucopyranosyl-2-beta-D-fructofuranoside
- Beet sugar
- Cane sugar
- Sacarosa
- Saccharose
- Sacharose
- Sucraloxum
- Sucrose
- Table sugar
- White sugar
- External IDs
- GNE-410
- NSC-406942
- S-67F
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Therapies
- Contraindications & Blackbox Warnings
- Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API
- Pharmacodynamics
Not Available
- Mechanism of action
Target Actions Organism ABeta-lactamase inhibitorStaphylococcus aureus UTaste receptor type 1 member 2 Not Available Humans UBeta-lactamase Not Available Escherichia coli (strain K12) ULysozyme C Not Available Humans UActin, alpha skeletal muscle Not Available Humans UBeta-glucosidase Not Available Streptomyces sp. UAmylosucrase Not Available Neisseria polysaccharea UBeta-lactamase Not Available Escherichia coli UBeta-lactamase CTX-M Not Available Escherichia coli UHeme oxygenase Not Available Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis) UCopper transport protein ATOX1 Not Available Humans URNA-splicing ligase RtcB homolog Not Available Humans UOrange carotenoid-binding protein Not Available Arthrospira maxima USucrose porin Not Available Salmonella typhimurium ULevansucrase Not Available Bacillus subtilis (strain 168) - Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Childrens Emetrol Cherry Sucrose (3.74 g/5mL) + Phosphoric acid (21.5 mg/5mL) Solution Oral WellSpring Pharmaceutical Corporation 2012-11-05 2012-11-01 US Childrens Emetrol Dye Free Grape Sucrose (3.74 g/5mL) + Phosphoric acid (21.5 mg/5mL) Solution Oral Well Spring Pharmaceutical Corporation 2013-04-21 2016-09-30 US Emetrol Cherry Sucrose (3.74 g/5mL) + Phosphoric acid (21.5 mg/5mL) Solution Oral Preferreed Pharmaceuticals Inc. 2012-04-23 Not applicable US Select Brand Anti-Nausea Sucrose (3.74 g/5mL) + Phosphoric acid (21.5 mg/5mL) Solution Oral L&R Distributors, Inc. 2008-01-01 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Childrens Emetrol Cherry Sucrose (3.74 g/5mL) + Phosphoric acid (21.5 mg/5mL) Solution Oral WellSpring Pharmaceutical Corporation 2012-11-05 2012-11-01 US Childrens Emetrol Dye Free Grape Sucrose (3.74 g/5mL) + Phosphoric acid (21.5 mg/5mL) Solution Oral Well Spring Pharmaceutical Corporation 2013-04-21 2016-09-30 US Emetrol Cherry Sucrose (3.74 g/5mL) + Phosphoric acid (21.5 mg/5mL) Solution Oral Preferreed Pharmaceuticals Inc. 2012-04-23 Not applicable US Select Brand Anti-Nausea Sucrose (3.74 g/5mL) + Phosphoric acid (21.5 mg/5mL) Solution Oral L&R Distributors, Inc. 2008-01-01 Not applicable US
Categories
- Drug Categories
- Carbohydrates
- Compounds used in a research, industrial, or household setting
- Diet, Food, and Nutrition
- Dietary Carbohydrates
- Dietary Sugars
- Disaccharides
- Flavoring Agents
- Food
- Food Additives
- Food Ingredients
- Nutritive Sweeteners
- Oligosaccharides
- Physiological Phenomena
- Polysaccharides
- Sweetening Agents
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as o-glycosyl compounds. These are glycoside in which a sugar group is bonded through one carbon to another group via a O-glycosidic bond.
- Kingdom
- Organic compounds
- Super Class
- Organic oxygen compounds
- Class
- Organooxygen compounds
- Sub Class
- Carbohydrates and carbohydrate conjugates
- Direct Parent
- O-glycosyl compounds
- Alternative Parents
- Disaccharides / C-glycosyl compounds / Ketals / Oxanes / Tetrahydrofurans / Secondary alcohols / Polyols / Oxacyclic compounds / Primary alcohols / Hydrocarbon derivatives
- Substituents
- Acetal / Alcohol / Aliphatic heteromonocyclic compound / C-glycosyl compound / Disaccharide / Hydrocarbon derivative / Ketal / O-glycosyl compound / Organoheterocyclic compound / Oxacycle
- Molecular Framework
- Aliphatic heteromonocyclic compounds
- External Descriptors
- glycosyl glycoside (CHEBI:17992) / Disaccharides (C00089)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- C151H8M554
- CAS number
- 57-50-1
- InChI Key
- CZMRCDWAGMRECN-UGDNZRGBSA-N
- InChI
- InChI=1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1
- IUPAC Name
- (2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
- SMILES
- OC[C@H]1O[C@@](CO)(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O
References
- Synthesis Reference
Francois B. Paul, Pierre F. Monsan, Magali M. C. Remaud, Vincent P. Pelenc, "Process for the enzymatic preparation from sucrose of a mixture of sugars having a high content of isomaltose, and products obtained." U.S. Patent US4861381, issued April, 1956.
US4861381- General References
- Ten S, Maclaren N: Insulin resistance syndrome in children. J Clin Endocrinol Metab. 2004 Jun;89(6):2526-39. [Article]
- Aguilera AA, Diaz GH, Barcelata ML, Guerrero OA, Ros RM: Effects of fish oil on hypertension, plasma lipids, and tumor necrosis factor-alpha in rats with sucrose-induced metabolic syndrome. J Nutr Biochem. 2004 Jun;15(6):350-7. [Article]
- Fukuchi S, Hamaguchi K, Seike M, Himeno K, Sakata T, Yoshimatsu H: Role of fatty acid composition in the development of metabolic disorders in sucrose-induced obese rats. Exp Biol Med (Maywood). 2004 Jun;229(6):486-93. [Article]
- Lombardo YB, Drago S, Chicco A, Fainstein-Day P, Gutman R, Gagliardino JJ, Gomez Dumm CL: Long-term administration of a sucrose-rich diet to normal rats: relationship between metabolic and hormonal profiles and morphological changes in the endocrine pancreas. Metabolism. 1996 Dec;45(12):1527-32. [Article]
- External Links
- Human Metabolome Database
- HMDB0000258
- KEGG Drug
- D00025
- KEGG Compound
- C00089
- PubChem Compound
- 5988
- PubChem Substance
- 46506134
- ChemSpider
- 5768
- BindingDB
- 50108105
- 10159
- ChEBI
- 17992
- ChEMBL
- CHEMBL253582
- ZINC
- ZINC000004217475
- PharmGKB
- PA451525
- RxList
- RxList Drug Page
- Wikipedia
- Sucrose
- PDB Entries
- 1a0t / 1ex2 / 1fe0 / 1fe4 / 1fee / 1gnx / 1iw0 / 1iw1 / 1jcq / 1jgi … show 255 more
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample dataNot Available Completed Not Available Tick Borne Encephalitis (TBE) 1 somestatus stop reason just information to hide Not Available Completed Basic Science Critically Ill Patients 1 somestatus stop reason just information to hide Not Available Completed Supportive Care Post Procedural Pain Management in Neonates 1 somestatus stop reason just information to hide Not Available Completed Treatment ICU Anemia / Trauma 1 somestatus stop reason just information to hide Not Available Completed Treatment Pain 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Tablet, chewable Oral Solution Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
Property Value Source melting point (°C) 185.5 °C PhysProp water solubility 2.1E+006 mg/L (at 25 °C) YALKOWSKY,SH & DANNENFELSER,RM (1992) logP -3.70 HANSCH,C ET AL. (1995) Caco2 permeability -5.77 ADME Research, USCD pKa 12.6 MERCK INDEX (1996) - Predicted Properties
Property Value Source Water Solubility 824.0 mg/mL ALOGPS logP -2.6 ALOGPS logP -4.5 Chemaxon logS 0.38 ALOGPS pKa (Strongest Acidic) 11.84 Chemaxon pKa (Strongest Basic) -3 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 11 Chemaxon Hydrogen Donor Count 8 Chemaxon Polar Surface Area 189.53 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 68.77 m3·mol-1 Chemaxon Polarizability 31.04 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
Property Value Probability Human Intestinal Absorption - 0.8682 Blood Brain Barrier + 0.7245 Caco-2 permeable - 0.8957 P-glycoprotein substrate Non-substrate 0.6386 P-glycoprotein inhibitor I Non-inhibitor 0.8721 P-glycoprotein inhibitor II Non-inhibitor 0.9402 Renal organic cation transporter Non-inhibitor 0.8146 CYP450 2C9 substrate Non-substrate 0.8747 CYP450 2D6 substrate Non-substrate 0.8561 CYP450 3A4 substrate Non-substrate 0.6536 CYP450 1A2 substrate Non-inhibitor 0.9425 CYP450 2C9 inhibitor Non-inhibitor 0.9377 CYP450 2D6 inhibitor Non-inhibitor 0.9395 CYP450 2C19 inhibitor Non-inhibitor 0.8821 CYP450 3A4 inhibitor Non-inhibitor 0.9716 CYP450 inhibitory promiscuity Low CYP Inhibitory Promiscuity 0.9258 Ames test Non AMES toxic 0.9132 Carcinogenicity Non-carcinogens 0.9565 Biodegradation Not ready biodegradable 0.7256 Rat acute toxicity 1.0936 LD50, mol/kg Not applicable hERG inhibition (predictor I) Weak inhibitor 0.9633 hERG inhibition (predictor II) Non-inhibitor 0.883
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 181.4756044 predictedDarkChem Lite v0.1.0 [M-H]- 161.3265975 predictedDarkChem Standard v0.1.0 [M-H]- 181.8531044 predictedDarkChem Lite v0.1.0 [M-H]- 182.8732044 predictedDarkChem Lite v0.1.0 [M-H]- 184.9806044 predictedDarkChem Lite v0.1.0 [M-H]- 171.58557 predictedDeepCCS 1.0 (2019) [M+H]+ 184.8773044 predictedDarkChem Lite v0.1.0 [M+H]+ 181.9849044 predictedDarkChem Lite v0.1.0 [M+H]+ 178.9284044 predictedDarkChem Lite v0.1.0 [M+H]+ 184.8272044 predictedDarkChem Lite v0.1.0 [M+H]+ 185.2058044 predictedDarkChem Lite v0.1.0 [M+H]+ 173.70934 predictedDeepCCS 1.0 (2019) [M+Na]+ 182.3283044 predictedDarkChem Lite v0.1.0 [M+Na]+ 176.2526701 predictedDarkChem Standard v0.1.0 [M+Na]+ 180.4032044 predictedDarkChem Lite v0.1.0 [M+Na]+ 182.6472044 predictedDarkChem Lite v0.1.0 [M+Na]+ 184.5404044 predictedDarkChem Lite v0.1.0 [M+Na]+ 179.71196 predictedDeepCCS 1.0 (2019)
Targets
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1. DetailsBeta-lactamase
- Kind
- Protein
- Organism
- Staphylococcus aureus
- Pharmacological action
- Yes
- Actions
- Inhibitor
- General Function
- Not Available
- Specific Function
- beta-lactamase activity
- Gene Name
- blaZ
- Uniprot ID
- P00807
- Uniprot Name
- Beta-lactamase
- Molecular Weight
- 31348.98 Da
References
- Zhou Y, Zhang Y, Zhao D, Yu X, Shen X, Zhou Y, Wang S, Qiu Y, Chen Y, Zhu F: TTD: Therapeutic Target Database describing target druggability information. Nucleic Acids Res. 2024 Jan 5;52(D1):D1465-D1477. doi: 10.1093/nar/gkad751. [Article]
2. DetailsTaste receptor type 1 member 2
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners
- Specific Function
- G protein-coupled receptor activity
- Gene Name
- TAS1R2
- Uniprot ID
- Q8TE23
- Uniprot Name
- Taste receptor type 1 member 2
- Molecular Weight
- 95182.54 Da
References
- Servant G, Tachdjian C, Tang XQ, Werner S, Zhang F, Li X, Kamdar P, Petrovic G, Ditschun T, Java A, Brust P, Brune N, DuBois GE, Zoller M, Karanewsky DS: Positive allosteric modulators of the human sweet taste receptor enhance sweet taste. Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4746-51. doi: 10.1073/pnas.0911670107. Epub 2010 Feb 19. [Article]
3. DetailsBeta-lactamase
- Kind
- Protein
- Organism
- Escherichia coli (strain K12)
- Pharmacological action
- Unknown
- General Function
- Class C beta-lactamase which confers resistance to penicillins and cephalosporins (PubMed:12323371, PubMed:17956081, PubMed:33199391, PubMed:6998377). Has benzylpenicillin- and cephaloridine-hydrolyzing activity (PubMed:3264154, PubMed:3264155, PubMed:6998377). Has weak cefuroxime, cefotaxime, cefoxitin and oxacillin-hydrolyzing activities (PubMed:3264154, PubMed:3264155).
- Specific Function
- beta-lactamase activity
- Gene Name
- ampC
- Uniprot ID
- P00811
- Uniprot Name
- Beta-lactamase
- Molecular Weight
- 41555.3 Da
References
4. DetailsLysozyme C
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents
- Specific Function
- identical protein binding
- Gene Name
- LYZ
- Uniprot ID
- P61626
- Uniprot Name
- Lysozyme C
- Molecular Weight
- 16536.885 Da
References
- Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [Article]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [Article]
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
5. DetailsActin, alpha skeletal muscle
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells
- Specific Function
- ADP binding
- Gene Name
- ACTA1
- Uniprot ID
- P68133
- Uniprot Name
- Actin, alpha skeletal muscle
- Molecular Weight
- 42050.67 Da
References
- Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [Article]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [Article]
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
6. DetailsBeta-glucosidase
- Kind
- Protein
- Organism
- Streptomyces sp.
- Pharmacological action
- Unknown
- General Function
- Not Available
- Specific Function
- beta-glucosidase activity
- Gene Name
- bgl3
- Uniprot ID
- Q59976
- Uniprot Name
- Beta-glucosidase
- Molecular Weight
- 52382.78 Da
7. DetailsAmylosucrase
- Kind
- Protein
- Organism
- Neisseria polysaccharea
- Pharmacological action
- Unknown
- General Function
- Catalyzes the synthesis of alpha-glucan from sucrose. Catalyzes, in addition, sucrose hydrolysis, maltose and maltotriose synthesis by successive transfers of the glucosyl moiety of sucrose onto the released glucose, and finally turanose and trehalulose synthesis, these two sucrose isomers being obtained by glucosyl transfer onto fructose.
- Specific Function
- amylosucrase activity
- Gene Name
- ams
- Uniprot ID
- Q9ZEU2
- Uniprot Name
- Amylosucrase
- Molecular Weight
- 72343.005 Da
8. DetailsBeta-lactamase
- Kind
- Protein
- Organism
- Escherichia coli
- Pharmacological action
- Unknown
- General Function
- Not Available
- Specific Function
- beta-lactamase activity
- Gene Name
- blaCTX-M-9a
- Uniprot ID
- Q9L5C8
- Uniprot Name
- Beta-lactamase
- Molecular Weight
- 30951.03 Da
References
- Bowden GA, Georgiou G: Folding and aggregation of beta-lactamase in the periplasmic space of Escherichia coli. J Biol Chem. 1990 Oct 5;265(28):16760-6. [Article]
9. DetailsBeta-lactamase CTX-M (Protein Group)
- Kind
- Protein group
- Organism
- Escherichia coli
- Pharmacological action
- Unknown
- General Function
- Not Available
- Specific Function
- beta-lactamase activity
Components:
10. DetailsHeme oxygenase
- Kind
- Protein
- Organism
- Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
- Pharmacological action
- Unknown
- General Function
- Allows the bacteria to use the host heme as an iron source. Involved in the oxidation of heme and subsequent release of iron from the heme moiety.
- Specific Function
- heme binding
- Gene Name
- hmuO
- Uniprot ID
- P71119
- Uniprot Name
- Heme oxygenase
- Molecular Weight
- 24115.81 Da
11. DetailsCopper transport protein ATOX1
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense
- Specific Function
- copper chaperone activity
- Gene Name
- ATOX1
- Uniprot ID
- O00244
- Uniprot Name
- Copper transport protein ATOX1
- Molecular Weight
- 7401.575 Da
12. DetailsRNA-splicing ligase RtcB homolog
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs
- Specific Function
- GTP binding
- Gene Name
- RTCB
- Uniprot ID
- Q9Y3I0
- Uniprot Name
- RNA-splicing ligase RtcB homolog
- Molecular Weight
- 55209.95 Da
References
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
13. DetailsOrange carotenoid-binding protein
- Kind
- Protein
- Organism
- Arthrospira maxima
- Pharmacological action
- Unknown
- General Function
- Acts as a blue-light photoreceptor and photo-protectant. Essential for inhibiting damaged induced by excess blue-green light via a process known as non-photochemical quenching (NPQ). Binding carotenoids improves OCP's intrinsic photoprotectant activity by broadening its absorption spectrum and facilitating the dissipation of absorbed energy (PubMed:15751975). In the dark or dim light the stable inactive form (OCP-O) is orange, upon illumination with blue-green light it converts to a metastable active red form (OCP-R), inducing energy dissipation, quenching cellular fluorescence via NPQ (By similarity).
- Specific Function
- chloride ion binding
- Gene Name
- Not Available
- Uniprot ID
- P83689
- Uniprot Name
- Orange carotenoid-binding protein
- Molecular Weight
- 35347.29 Da
14. DetailsSucrose porin
- Kind
- Protein
- Organism
- Salmonella typhimurium
- Pharmacological action
- Unknown
- General Function
- Porin for sucrose uptake.
- Specific Function
- carbohydrate transmembrane transporter activity
- Gene Name
- scrY
- Uniprot ID
- P22340
- Uniprot Name
- Sucrose porin
- Molecular Weight
- 55466.87 Da
15. DetailsLevansucrase
- Kind
- Protein
- Organism
- Bacillus subtilis (strain 168)
- Pharmacological action
- Unknown
- General Function
- Catalyzes the synthesis of levan, a fructose polymer, by transferring the fructosyl moiety from sucrose to a growing acceptor molecule (PubMed:14517548, PubMed:18596022, PubMed:32553967, PubMed:33303628, PubMed:4206083). Also displays sucrose hydrolase activity (PubMed:18596022, PubMed:32553967, PubMed:33303628, PubMed:4206083). At low sucrose concentrations, functions as an hydrolase with water as acceptor, whereas at higher substrate concentrations it adds fructosyl units to a growing levan chain (PubMed:4206083).
- Specific Function
- levansucrase activity
- Gene Name
- sacB
- Uniprot ID
- P05655
- Uniprot Name
- Levansucrase
- Molecular Weight
- 52970.73 Da
Drug created at June 13, 2005 13:24 / Updated at August 26, 2024 19:22