Copper transport protein ATOX1

BE0002833ProteinHumansATOX1

Multifunctional copper-sensing protein that operates both as a cytosolic copper chaperone and as a copper-dependent transcription factor. It is acted on by 4 drugs in DrugBank.

Gene name
ATOX1
UniProtKB entry
O00244Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
68 residues · 7,402 Da
Also known as
HAH1 · Metal transport protein ATX1

Resolves to

Protein
UniProtO00244UniProt nameATOX1_HUMAN
Gene
HGNCHGNC:798NCBI Gene475GeneCardsATOX1
Pharmacology
KEGGhsa:475
Structure
PDB1FE0PDB1FE4PDB1FEE
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Copper transport protein ATOX1, how selective are they, and which programs against it are still in active trials?

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