Flavohemoprotein

BE0002917ProteinEscherichia coli (strain K12)hmp

Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. It is acted on by 1 drug in DrugBank.

Gene name
hmp
UniProtKB entry
P24232Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
396 residues · 43,867 Da
Also known as
Flavohemoglobin · fsrB · Hemoglobin-like protein · HMP · hmpA

Resolves to

Protein
UniProtP24232UniProt nameHMP_ECOLI
Gene
NCBI Gene947018
Pharmacology
KEGGecj:JW2536
Structure
PDB1GVH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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37+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Flavohemoprotein, how selective are they, and which programs against it are still in active trials?

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