C-C motif chemokine 8

BE0002941ProteinHumansCCL8

Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. It is acted on by 2 drugs in DrugBank.

Gene name
CCL8
UniProtKB entry
P80075Swiss-Prot
Cellular location
Secreted
Residues / weight
99 residues · 11,246 Da
Also known as
HC14 · MCP-2 · MCP2 · Monocyte chemoattractant protein 2 · Monocyte chemotactic protein 2

Resolves to

Protein
UniProtP80075UniProt nameCCL8_HUMAN
Gene
HGNCHGNC:10635NCBI Gene6355GeneCardsCCL8
Pharmacology
KEGGhsa:6355
Structure
PDB1ESRPDB7S59PDB7S5A
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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15GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on C-C motif chemokine 8, how selective are they, and which programs against it are still in active trials?

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