Intron-associated endonuclease 1

BE0002953ProteinEnterobacteria phage T4ITEVIR

This endonuclease is specific to the thymidylate synthase (td) gene splice junction and is involved in intron homing. It is acted on by 1 drug in DrugBank.

Gene name
ITEVIR
UniProtKB entry
P13299Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
245 residues · 28,232 Da
Also known as
3.1.-.- · I-TevI · IRF protein

Resolves to

Protein
UniProtP13299UniProt nameTEV1_BPT4
Gene
NCBI Gene1258722
Pharmacology
KEGGvg:1258722
Structure
PDB1I3JPDB1LN0PDB1MK0
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Intron-associated endonuclease 1, how selective are they, and which programs against it are still in active trials?

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