Dimethylglycine oxidase

BE0002961ProteinArthrobacter globiformisdmg

Catalyzes the oxidative demethylation of N,N-dimethylglycine to yield sarcosine, formaldehyde and hydrogen peroxide. It is acted on by 2 drugs in DrugBank.

Gene name
dmg
UniProtKB entry
Q9AGP8Swiss-Prot
Residues / weight
830 residues · 89,984 Da
Also known as
1.5.3.10 · DMGO

Resolves to

Protein
UniProtQ9AGP8UniProt nameDMGO_ARTGO
Structure
PDB1PJ5PDB1PJ6PDB1PJ7
Drugs

What you can answer from here — as of September 04, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Dimethylglycine oxidase, how selective are they, and which programs against it are still in active trials?

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