Pyrroloquinoline-quinone synthase

BE0003016ProteinKlebsiella pneumoniaepqqC

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ. It is acted on by 1 drug in DrugBank.

Gene name
pqqC
UniProtKB entry
P27505Swiss-Prot
Residues / weight
251 residues · 28,986 Da
Also known as
1.3.3.11 · Coenzyme PQQ synthesis protein C · Pyrroloquinoline quinone biosynthesis protein C

Resolves to

Protein
UniProtP27505UniProt namePQQC_KLEPN
Structure
PDB1OTVPDB1OTW
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Pyrroloquinoline-quinone synthase, and which indications are they being tested in?

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