NAD(P)H-dependent nitroreductase NfsB

BE0003031ProteinEnterobacter cloacaenfsB

Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. It is acted on by 2 drugs in DrugBank.

Gene name
nfsB
UniProtKB entry
Q01234Swiss-Prot
Residues / weight
217 residues · 23,950 Da
Also known as
1.-.-.- · 1.7.1.- · NAD(P)H-dependent quinone reductase · nfnB · nfsI

Resolves to

Protein
UniProtQ01234UniProt nameNFSB_ENTCL
Structure
PDB1KQBPDB1KQCPDB1KQD
Drugs

What you can answer from here — as of September 08, 2026

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which approved drugs act on NAD(P)H-dependent nitroreductase NfsB, how selective are they, and which programs against it are still in active trials?

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