NADH dehydrogenase

BE0003040ProteinThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)nox

Can oxidize either NADH or NADPH with a preference for NADH. It is acted on by 2 drugs in DrugBank.

Gene name
nox
UniProtKB entry
Q60049Swiss-Prot
Residues / weight
205 residues · 22,730 Da
Also known as
1.6.99.3 · 7.1.1.2 · H(2)O(2)-forming NADH oxidase · NADH:oxygen oxidoreductase

Resolves to

Protein
UniProtQ60049UniProt nameNOX_THET8
Gene
NCBI Gene3168975
Pharmacology
KEGGttj:TTHA0425
Structure
PDB1NOX
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which approved drugs act on NADH dehydrogenase, how selective are they, and which programs against it are still in active trials?

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