Phosphopantothenoylcysteine decarboxylase

BE0003043ProteinHumansPPCDC

Catalyzes the decarboxylation of the cysteine moiety of 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine and this reaction forms part of the biosynthesis of coenzyme A. It is acted on by 2 drugs in DrugBank.

Gene name
PPCDC
UniProtKB entry
Q96CD2Swiss-Prot
Residues / weight
204 residues · 22,395 Da
Also known as
4.1.1.36 · COAC · PPC-DC

Resolves to

Protein
UniProtQ96CD2UniProt nameCOAC_HUMAN
Gene
HGNCHGNC:28107NCBI Gene60490GeneCardsPPCDC
Pharmacology
KEGGhsa:60490
Structure
PDB1QZU
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Phosphopantothenoylcysteine decarboxylase, how selective are they, and which programs against it are still in active trials?

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